Search on: APC1 SUBUNIT, ANAPHASE-PROMOTING COMPLEX-CYCLOSOME 
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Descriptor English:   Apc1 Subunit, Anaphase-Promoting Complex-Cyclosome 
Descriptor Spanish:   Subunidad Apc1 del Ciclosoma-Complejo Promotor de la Anafase 
Descriptor Portuguese:   Subunidade Apc1 do Ciclossomo-Complexo Promotor de Anáfase 
Tree Number:   D08.811.464.938.750.092.500
D12.776.167.024.500
Definition English:   The largest subunit of the anaphase-promoting complex. It acts primarily as a scaffold for the proper organization and arrangement of subunits. The C-terminal region of Apc1 contains a series of tandem amino acid repeats that are also seen in the 26S proteasome regulatory particle, and may assist with forming and stabilizing protein-protein interactions. 
History Note English:   2014 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification CT contraindications
DF deficiency DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects SE secretion
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Record Number:   55273 
Unique Identifier:   D064189 

Occurrence in VHL:
 

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